• MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • 30 DAY MONEY BACK GUARANTEE

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • 30 DAY MONEY BACK GUARANTEE

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • 30 DAY MONEY BACK GUARANTEE

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • 30 DAY MONEY BACK GUARANTEE

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • 30 DAY MONEY BACK GUARANTEE

Coffee's Real Secret

Boost NAD+ for Strength, Focus, and Vitality—No Jitters, Just Results.

Trigonelline

Backed by 2024 Nature Metabolism study
Regular price $44.95 Sale price $44.95

Supports Muscle Growth & Strength – Plays a role in cellular repair and protein synthesis, which can contribute to muscle hypertrophy and strength gains over time.

Increases NAD+ Levels in Muscle Tissue
 – NAD+ is an essential molecule for cellular energy production (ATP synthesis), helping sustain endurance and reducing muscle fatigue during exercise.

Enhances Mitochondrial Efficiency – Supports mitochondrial function, allowing for greater energy output and improved muscular endurance.

Reduces Muscle Fatigue – Helps delay muscle exhaustion by optimizing oxygen utilization and minimizing metabolic waste accumulation, such as lactate.

Promotes Faster Recovery
 – Aids in reducing inflammation and oxidative stress post-exercise, accelerating muscle repair and reducing soreness.

Improves Oxygen Utilization – Enhances red blood cell efficiency, which supports better oxygen delivery to muscles, leading to increased stamina and performance.

Enhance Glucose Uptake – Improves how cells absorb and utilize glucose, leading to better energy production and reduced blood sugar spikes.

Improve Insulin Sensitivity – Helps cells respond more effectively to insulin, potentially lowering the risk of insulin resistance and type 2 diabetes.

Support Healthy Lipid Metabolism – May aid in reducing excess fat accumulation and improving cholesterol levels, contributing to overall metabolic health.

Regulate Glycogen Storage – Promotes efficient storage and utilization of glycogen in muscles and the liver, which is essential for sustained energy levels.

Trigonelline plays a role in maintaining brain health and cognitive function by supporting neuronal energy production, neuroprotection, and reducing neuroinflammation.

Enhances NAD+ for Brain Function – NAD+ is essential for mitochondrial function in neurons, supporting cognitive processes like memory, learning, and focus.

Supports Neuroprotection – Helps protect brain cells from damage caused by oxidative stress and neurotoxins, potentially reducing the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's.

Reduces Neuroinflammation – May lower inflammation in the brain, which is associated with cognitive decline and brain fog.

Supports Synaptic Plasticity – May enhance communication between neurons, improving learning, memory retention, and cognitive flexibility.

Improves Cerebral Blood Flow – Supports healthy circulation to the brain, ensuring adequate oxygen and nutrient delivery for optimal function.

Regulates Mood and Wellbeing  – May influence key neurotransmitters like acetylcholine, dopamine, and serotonin, which are critical for mood, focus, and mental clarity.

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Unlock Energy, endurance, and focus

Naturally found in coffee, Trigonelline is a powerful compound you've likely already benefited from—now available in its purest, most concentrated form.

As a direct NAD+ precursor, it supports brain health, energy, endurance, and metabolic function, helping you perform at your peak. Backed by emerging research and trusted by longevity enthusiasts, our 300mg Trigonelline capsules deliver clean, effective support—without the jitters of caffeine.

Experience the science of better aging, performance, and vitality—one capsule at a time.

Trigonelline Research
Science-Backed Results

Trigonelline Supplement Research

Customer Reviews

Based on 5 reviews
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Brandon
Pure Performance

Been taking this supplement for a little bit now and immediately noticed the difference in energy levels and focus. It's helped my performance in the gym and gives me just the right amount of energy to get through my workouts without the crash. Great supplement!

H
Hamza
Can't believe I waited so long to try it!

I’ve been using trigonelline for a few months now, and it’s made a noticeable difference across the board. In the gym, I’ve seen steady improvements in strength and performance, and outside of it, I feel sharper and more focused at work. No jitters, no crash—just clean, sustained energy and better mental clarity. Definitely one of those supplements that quietly works in the background and delivers real results over time. Highly recommend giving it a try.

J
Jacob
Noticeable difference on the job

I noticed a difference in my energy levels especially on long landscaping days. When I’m doing physical work like digging or hauling, it helps me push through without burning out. That said, I wouldn’t take it on a rest day. It gives me more energy than I know what to do with.

J
Jason M
The endurance...

I went on a 6 mile hike, first hike of the year, not expecting much. Wow. I was quite literally bouncing off the trail like a billy goat and running circles around my friends. That was day 1 taking trigonelline. I was not expecting instant results.. very impressed!

A
Alex
Incredible! A Genuine Increase in Endurance

Small pill, easy to take. The promise of increased endurance with Trigonelline seemed great, but I had no expectations because it appears that many supplements promise this benefit. Anyway, I have been going to F-45 for HIIT since August 2021. Today I took two capsules (oops, the back of the bottle says only one). In short, the noticeable improvement in endurance is genuine. That was instantly recognizable. Even before the gym, as it was getting into my system, I could feel the energy without the jitters, just as advertised. It is a pleasant surprise when a product lives up to its promise!

So I get to F-45 today, and my endurance has suddenly improved, whereas previously I felt more exhausted between workout stations. I texted my wife shortly afterwards, completely impressed... I will attach the screenshot, which speaks for itself—sort of—with the voice-to-text spelling errors...

All of this to say that if you are someone who constantly pushes themselves to the limit, like me, and participates in a workout or physically demanding routine, such as high-intensity interval training, I am confident you will see a significant difference. Trigonelline appears to perform exceptionally well under heavy loads. It also appears to have other benefits, but for the time being, I recommend that you go to the gym and give it a try.