Strength and Endurance

Support strength and recovery by increasing NAD+ levels in muscle tissue

Metabolic Health

Help regulate blood sugar and improve insulin sensitivity. 

Energy and cognition

Reduces neuroinflamation and protects against cognitive decline

Learn More

MADE IN USA
GMP CERTIFIED
THIRD PARTY TESTED
ZERO FILLERS

MADE IN USA
GMP CERTIFIED
THIRD PARTY TESTED
ZERO FILLERS

MADE IN USA
GMP CERTIFIED
THIRD PARTY TESTED
ZERO FILLERS

MADE IN USA
GMP CERTIFIED
THIRD PARTY TESTED
ZERO FILLERS

MADE IN USA
GMP CERTIFIED
THIRD PARTY TESTED
ZERO FILLERS

NATURALLY FOUND IN COFFEE

Unlock Energy, endurance, and focus.

Naturally found in coffee, Trigonelline is a powerful compound you've likely already benefited from—now available in its purest, most concentrated form. As a direct NAD+ precursor, it supports brain health, energy, endurance, and metabolic function, helping you perform at your peak. Backed by emerging research and trusted by longevity enthusiasts, our 300mg Trigonelline capsules deliver clean, effective support—without the jitters of caffeine. Experience the science of better aging, performance, and vitality—one capsule at a time.

Shop Trigonelline

Defy Human Potential.

At Mortalis Labs, we believe human potential is only beginning to be understood. Our formulations are built with clinical precision, led by breakthrough molecules like Trigonelline — compounds that don’t just support performance but redefine it. We are not in the business of “good enough.” We exist to serve those who chase the edge of what's possible — and then keep going. Because greatness is not given. It’s built. It’s earned.

Backed by science

Recent studies have revealed exciting discoveries about Trigonelline’s potential benefits for health, performance and therapeutic applications.

The Complete Benefits of Trigonelline: Cognitive Clarity, Strength, and Cellular Resilience

Recent research reveals Trigonelline's role as a direct NAD⁺ precursor that supports everything from mental clarity to mitochondrial biogenesis, muscle strength to metabolic health. Unlike older precursors like NR or...

Trigonelline and the Brain: NAD+, Neuroprotection, and Cognitive Precision

Trigonelline restores NAD⁺ directly in brain tissue. In the Nature Metabolism 2024 study, trigonelline was detected in cerebrospinal fluid, confirming central nervous system uptake - a level of access most...

Trigonelline for Peak Performance: The Molecule for Powering Strength, Endurance, and Recovery

Recent Trigonelline research published on this naturally occurring alkaloid highlights its potential in enhancing muscle function and combating age-related decline.

Trigonelline and Muscle Health: Insights from Nestlé's Research

A 2024 study published in Nature Metabolism, conducted by researchers from EPFL in collaboration with the Nestlé Institute of Health Sciences identifies Trigonelline as a novel precursor to NAD+, a...

I have more energy, recover faster, and sleep better!!

Since starting Trigonelline my running is improving at a fast rate considering I am 76 years old. I may now train for half marathon!! I love it!!

Product definitely helps me focus

Just received order yesterdayu

Deceptively clean energy

It’s almost too clean. I don’t notice having more energy during the day. But at the end of the day I realize… OH. Wow. I got all my work done and I didn’t feel tired at all or like I needed a nap as I usually do. So yes this stuff works but it’s the kind of energy you don’t necessarily notice. Trigonelline is not like taking pre-workout powder. It’s like upgrading your brain. Very cool. As far as endurance, yes I’m impressed. This is not placebo. I’ve been staying at the gym longer, doing more weight and more sets, and I haven’t needed my inhaler during cardio. That last part is especially awesome.