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Unlock your body’s potential with Trigonelline.

Trigonelline Is the Molecule Athletes Should Be Watching. Unparalleled Strength and endurance. Metabolism. Cognition. You're ready to reach new peaks.

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NOW IN PURE FORM

BOOST NAD+ FOR STRENGTH, FOCUS, AND VITALITY—NO JITTERS, JUST RESULTS.

Naturally found in coffee, Trigonelline is a powerful compound you've likely already benefited from—now available in its purest, most concentrated form.

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Strength and Endurance

Support strength and recovery by increasing NAD+ levels in muscle tissue

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Metabolic Health

Help regulate blood sugar and improve insulin sensitivity.


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Energy and cognition

Reduces neuroinflamation and protects against cognitive decline

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  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

  • MADE IN USA

  • GMP CERTIFIED

  • THIRD PARTY TESTED

  • ZERO FILLERS

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NATURALLY FOUND IN COFFEE

Unlock Energy, endurance, and focus.

Naturally found in coffee, Trigonelline is a powerful compound you've likely already benefited from—now available in its purest, most concentrated form. As a direct NAD+ precursor, it supports brain health, energy, endurance, and metabolic function, helping you perform at your peak. Backed by emerging research and trusted by longevity enthusiasts, our 300mg Trigonelline capsules deliver clean, effective support—without the jitters of caffeine. Experience the science of better aging, performance, and vitality—one capsule at a time.

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Defy Human Potential.

At Mortalis Labs, we believe human potential is only beginning to be understood. Our formulations are built with clinical precision, led by breakthrough molecules like Trigonelline — compounds that don’t just support performance but redefine it. We are not in the business of “good enough.” We exist to serve those who chase the edge of what's possible — and then keep going. Because greatness is not given. It’s built. It’s earned.

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MORE THAN MORTAL.

Welcome to Mortalis Labs.

Built for the Unbreakable, The Relentless.

You feel it. That pulse beneath the surface whispering: not yet. Not enough. Not done.
Mortalis Labs exists for that voice — the one that pushes you forward when everything else tells you to stop. The reps no one sees. The recovery no one talks about. The obsession with becoming just 1% better every day.

More Than Mortal. 

You weren’t made to settle. Neither were we. Mortalis Labs was born for those who move with purpose. Our name — mortalis, Latin for “mortal” — is a reminder of what we are. But it’s also a challenge. To become something more. To become something more than mortal. 

Join the Movement. Train beyond limits. Recover beyond norms. Live more than mortal. 

The History of Trigonelline

1891
1950s
1970s
1980s - 1990s
2010 - 2025
BACKED BY SCIENCE

The Latest Trigonelline Research

Recent studies have revealed exciting discoveries about Trigonelline’s potential benefits for health, performance and therapeutic applications.
The Complete Benefits of Trigonelline: Cognitive Clarity, Strength, and Cellular Resilience

The Complete Benefits of Trigonelline: Cognitive Clarity, Strength, and Cellular Resilience

By Mortalis Labs May 22, 2025

Recent research reveals Trigonelline's role as a direct NAD⁺ precursor that supports everything from mental clarity to mitochondrial biogenesis, muscle strength to metabolic health. Unlike older precursors like NR or...

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Trigonelline and the Brain: NAD+, Neuroprotection, and Cognitive Precision

Trigonelline and the Brain: NAD+, Neuroprotection, and Cognitive Precision

By Mortalis Labs May 22, 2025

Trigonelline restores NAD⁺ directly in brain tissue. In the Nature Metabolism 2024 study, trigonelline was detected in cerebrospinal fluid, confirming central nervous system uptake - a level of access most...

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Trigonelline for Peak Performance: The Molecule for Powering Strength, Endurance, and Recovery

Trigonelline for Peak Performance: The Molecule for Powering Strength, Endurance, and Recovery

By Mortalis Labs May 22, 2025

Recent Trigonelline research published on this naturally occurring alkaloid highlights its potential in enhancing muscle function and combating age-related decline.

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Trigonelline and Muscle Health: Insights from Nestlé's Research

Trigonelline and Muscle Health: Insights from Nestlé's Research

By Mortalis Labs May 22, 2025

A 2024 study published in Nature Metabolism, conducted by researchers from EPFL in collaboration with the Nestlé Institute of Health Sciences identifies Trigonelline as a novel precursor to NAD+, a...

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Customer Reviews

Based on 9 reviews
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Billy Carson Taylor
I have more energy, recover faster, and sleep better!!

Since starting Trigonelline my running is improving at a fast rate considering I am 76 years old. I may now train for half marathon!! I love it!!

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Shawn

Great energy.

S
S.A.
Great energy boost without the crash

I’ve been taking this trigonelline supplement for a couple of weeks and really like it. I feel more focused and energized throughout the day, without any jittery feeling or crash. Definitely a nice, clean boost!

J
James G
Fantastic Energy, No crash

My first time using Trigonelline was impressive! I had more energy for longer than two cups of coffee and my attention to detail was top notch. I couldn't recommend this product more. I've already told my family and friends about it and hopefully his review will help you too!

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Brandon
Pure Performance

Been taking this supplement for a little bit now and immediately noticed the difference in energy levels and focus. It's helped my performance in the gym and gives me just the right amount of energy to get through my workouts without the crash. Great supplement!

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